The ChromoTek PARP1-Trap is an affinity resin for immunoprecipitation of PARP1.
It consists of an anti-PARP1 Nanobody/ VHH coupled to beads.
Human PARP1, does not bind to PARP2, 3, and 9
Epitope: within DNA binding domain of PARP1.
Immunoprecipitation (IP) / Co-IP
Mass spectrometry (MS)
On-bead enzyme assays
PARP1 Nanobody, PARP1 VHH, Binding-Protein, or single domain antibody fragment (sdAb)
Benefit from PARP1-Trap for Immunoprecipitation (IP)
- Effectively immunoprecipitates PARP1 (human)
- Functional after IP: on-bead parylation assay
- No heavy & light chains in your downstream application
Format/matrices & properties
Extraordinary stable & reliable binding
- Fully applications validated and characterized
Poly (ADP-ribose) polymerase 1 (PARP1) is one of the most abundant proteins in the nucleus and is involved in many cellular processes like DNA repair, transcriptional regulation, and modulation of chromatin structure.
Only for research applications, not for diagnostic or therapeutic use!