PARP1-Trap
1
Description
The ChromoTek PARP1-Trap is an affinity resin for immunoprecipitation of PARP1.
It consists of an anti-PARP1 Nanobody/ VHH coupled to beads.
Specificity
Human PARP1, does not bind to PARP2, 3, and 9
Epitope: within DNA binding domain of PARP1.
Applications
Immunoprecipitation (IP) / Co-IP
Mass spectrometry (MS)
On-bead enzyme assays
Formats/matrices
PARP1-Trap Agarose
PARP1 VHH, recombinant binding protein
Synonyms
PARP1 Nanobody, PARP1 VHH, Binding-Protein, or single domain antibody fragment (sdAb)
Benefit from PARP1-Trap for Immunoprecipitation (IP)
- Effectively immunoprecipitates PARP1 (human)
- Functional after IP: on-bead parylation assay
- No heavy & light chains in your downstream application
Format/matrices & properties
We offer the PARP1 VHH coupled to agarose beads or uncoupled as purified protein.
Extraordinary stable & reliable binding
- Fully applications validated and characterized
About PARP1
Poly (ADP-ribose) polymerase 1 (PARP1) is one of the most abundant proteins in the nucleus and is involved in many cellular processes like DNA repair, transcriptional regulation, and modulation of chromatin structure.
Only for research applications, not for diagnostic or therapeutic use!