PARP1-Trap

Description
The ChromoTek PARP1-Trap is an affinity resin for immunoprecipitation of PARP1.
It consists of an anti-PARP1 Nanobody/ VHH coupled to beads.

Specificity
Human PARP1, does not bind to PARP2, 3, and 9
Epitope: within DNA binding domain of PARP1.

Applications
Immunoprecipitation (IP) / Co-IP
Mass spectrometry (MS)
On-bead enzyme assays

Formats/matrices
PARP1-Trap Agarose
PARP1 VHH, recombinant binding protein

Synonyms
PARP1 Nanobody, PARP1 VHH, Binding-Protein, or single domain antibody fragment (sdAb)

Benefit from PARP1-Trap for Immunoprecipitation (IP)

  • Effectively immunoprecipitates PARP1 (human)
  • Functional after IP: on-bead parylation assay
  • No heavy & light chains in your downstream application

Format/matrices & properties

We offer the PARP1 VHH coupled to agarose beads or uncoupled as purified protein.

Extraordinary stable & reliable binding

  • Fully applications validated and characterized

About PARP1

Poly (ADP-ribose) polymerase 1 (PARP1) is one of the most abundant proteins in the nucleus and is involved in many cellular processes like DNA repair, transcriptional regulation, and modulation of chromatin structure.

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Only for research applications, not for diagnostic or therapeutic use!