Intracellular Functional Antibodies or Intrabodies
ChromoTek’s Chromobodies® are fluorescent nanoprobes for real-time and live-cell imaging of intracellular endogenous proteins.
A Chromobody is a small intracellular functional antibody. It consists of a VHH/ Nanobody that is genetically fused to a fluorescent protein. Unlike conventional antibodies, Chromobodies visualize endogenous cellular structures and processes in live cells and real-time. Chromobody probes label non-invasively their targets without interfering with target function. This makes them perfect nanoprobes for cellular research and high content analysis.
Chromobody products comprise plasmids and selected stable cell lines.
The Chromobody technology is covered by granted and pending international patents.
Learn more about our Chromobody technology
|Code acr||Description Actin-Chromobody® plasmid (TagRFP)||Size 20 µg||Price $ 999|
|Code acg||Description Actin-Chromobody® plasmid (TagGFP2)||Size 20 µg||Price $ 999|
|Code acg-n||Description Nuclear Actin-Chromobody® plasmid (TagGFP2)||Size 20 µg||Price $ 999|
|Code ccr||Description Cell Cycle-Chromobody® plasmid (TagRFP)||Size 20 µg||Price $ 999|
|Code h-ccc-g||Description Frozen cells in FCS free cryopreservation reagent CryoMaxx||Size 5x 10^6 frozen cells||Price Please inquire|
|Code u-ccc-g||Description Frozen cells in FCS free cryopreservation reagent CryoMaxx||Size 5x 10^6 frozen cells||Price Please inquire|
|Code h-ccc-r||Description Frozen cells in FCS free cryopreservation reagent CryoMaxx||Size 5x 10^6 frozen cells||Price Please inquire|
High content analysis
High-content screening (HCS) comprises multiple cellular assays that are conducted in an automated, parallel manner to analyze a set of different biological parameters in live cells in a high throughput format. It is used in cell biology and drug discovery to find compounds that impact cellular processes, protein-protein interactions, and/or the phenotype of cells. Tested compounds include small molecules, peptides, and RNAi. Assays are usually based on fluorescence imaging. Next to automated microscopes for data acquisition also automated image analysis software is used, because huge data amounts are generated. HCS is also called high-content analysis (HCA) or cellomics.PRODUCTS
All Chromobodies are carefully selected to not interfere with endogenous protein function and offer the unique possibility to trace native proteins in living cells.
Only for research applications, not for diagnostic or therapeutic use!